Scientific Coworker

Photonic-based analysis of natural products in complex biosystems

 
Principal Investigator: J. Popp [Z02]

more information:  Dr. Petra Rösch: petra.roesch[a]uni-jena.de

Short description of the Job: The goal of this project within the CRC ChemBioSys is to develop and apply sensitive coherent Raman approaches in combination with other non-linear spectroscopic techniques to go a step further in the understanding of microbe interaction in consortia or with higher organisms. The non-linear spectroscopic techniques allow tracing selective molecular vibrations of lipids, proteins and DNA and other biological relevant targets with a high sensitivity on a subcellular level and a lateral resolution to the diffraction limit (~200 nm) while simultaneously enabling a 3D sectioning capability. Here, especially vibrational spectroscopic techniques will be used. Since naturally fluorescing components (autofluorophores) are ubiquity involved in metabolomic and signalling also fluorescence lifetime imaging microscopy (FLIM) is an option for the investigations.

Required Skills:

• A Master’s degree (or equivalent) in physical chemistry, physics, optics/photonics or a related discipline
• Solid knowledge of optical spectroscopy/microscopy and their application in materials sciences
• Excellent technical skills in laser (micro)spectroscopy with focus on vibrational spectroscopy
• Enthusiasm to play an active role in the interdisciplinary research team of ChemBioSys
• Highly motivated and creative personalities
• Excellent written and oral communications skills in English