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11.05.2023 by ChemBioSys
NEWS: Scientists “revive” Stone Age molecules
ChemBioSys publication:
In a highly transdisciplinary study, scientists are rebuilding microbial natural products up to 100,000 years old using dental calculus of humans and Neanderthals
Using ancient DNA, biochemists have succeeded in producing molecules - the paleofurans (shown here in powder form). Image: Anna Schroll/Leibniz-HKI
press release FSU: Scientists “revive” Stone Age molecules
Original-Publication:
Klapper M, Hübner A, Ibrahim A, Wasmuth I, Borry M, Haensch VG, Zhang S, Al-Jammal WK, Suma H, Fellows Yates JA, Frangenberg J, Velsko IM, Chowdhury S, Herbst R, Bratovanov EV, Dahse H-M, Horch T, Hertweck C, González Morales MR, Straus LG, Vilotijevic I, Warinner C, Stallforth P (2023): Natural products from reconstructed bacterial genomes of the Middle and Upper Paleolithic. Science, doi: 10.1126/science.adf5300